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SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 7 Reviews
8.7
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Folate (as L-5-Methyltetrahydrofolate calcium salt)
680 mcg°
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12,500%
Top Medical Research Studies
7
Folic acid reduces cholesterol risk
Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis.
Moderate relevance to cholesterol effects
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
8
Cholesterol reduction in children studied
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Folate's individual impact unclear
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
Most Useful Reviews
9.5
Boosts energy levels
I took this product to reduce high homocysteine and cholesterol levels as recommended by my doctor. It worked wonders—after two months, I felt more energetic and noted a decrease in homocysteine. The small capsules are easy to swallow, and I would buy this product again as it was effective for me.
Read More
9.5
Effective vitamin complex
This complex worked excellently for my husband to reduce his high homocysteine levels, which increase cardiovascular risks. After using it, his levels decreased significantly, confirmed by lab results. It's unfortunate that such vitamin forms are not readily available in pharmacies, as many doctors overlook this analysis in favour of statin prescriptions.
Read More
9.5
Highly recommended product
This product is fantastic for anyone with high homocysteine levels. I found it to be highly effective!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
8
Cholesterol reduction in children studied
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Folate's individual impact unclear
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
7
Folic acid reduces cholesterol risk
Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis.
Moderate relevance to cholesterol effects
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.7
9.5
Boosts energy levels
I took this product to reduce high homocysteine and cholesterol levels as recommended by my doctor. It worked wonders—after two months, I felt more energetic and noted a decrease in homocysteine. The small capsules are easy to swallow, and I would buy this product again as it was effective for me.
Read More
9.5
Effective vitamin complex
This complex worked excellently for my husband to reduce his high homocysteine levels, which increase cardiovascular risks. After using it, his levels decreased significantly, confirmed by lab results. It's unfortunate that such vitamin forms are not readily available in pharmacies, as many doctors overlook this analysis in favour of statin prescriptions.
Read More
9.5
Highly recommended product
This product is fantastic for anyone with high homocysteine levels. I found it to be highly effective!
9.5
Improved wellbeing
I’ve taken folate from this brand before. This formulation, which includes both B12 and folate, is easily digestible. I experienced high homocysteine levels initially, but thanks to this product, my levels normalised and my wellbeing improved without any side effects. I recommend it for its value and quality.
Read More
8.8
Reduced homocysteine levels
I ordered this drug for my elderly mother who has atherosclerosis and high cholesterol. The ultrasound showed atherosclerosis and further tests revealed high homocysteine as a contributing factor. High homocysteine levels can negatively affect vascular walls and contribute to cell death and blood clot formation. Folic acid and B12 lower homocysteine levels effectively. I found this product gentle and without side effects.
Read More
